110 new jobs are being created at Southport and Ormskirk Hospital Trust thanks to an extra £4 million Government funding.
Direct Line is closing its office in Liverpool. The firm is axing 2000 staff across the country - 485 of them on Merseyside.
Bury-based JD Sports Fashion warned it will shut more Blacks Leisure stores after a sharp fall in profits.
The UK's largest dry cleaning chain, Cheshire-based Johnson Service Group, is to axe more than a fifth of its stores this year, a move that will trigger hundreds of job losses.
Johnson Service Group said it will close 100 of its 460 Johnson Cleaners stores.
The new Northern Rail depot in Liverpool has created 46 jobs. The company says the facility will improve reliability and cut delays. It was officially opened this morning by Transport Minister Theresa Villiers.
Northern Rail say the new £10 million depot in Liverpool has created 46 new jobs, and will improve reliability and cut delays.
– Talk Talk statement
There will be significant new opportunities for existing employees at Preston, Stornoway and Warrington and TalkTalk will be working with affected employees to maximise opportunities to transfer to new roles and thereby minimise job losses in a year that, ultimately, will see more UK roles created than lost.
It is proposed the Northampton site will close after the restructuring is complete with approximately 200 new roles created at Preston through the appointment of a new strategic partner to manage the existing site and some of its operations.