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There have been some huge Manchester derbies in recent years. But the mouths have been watering for months over this.
With kick off around high noon tomorrow, it's the showdown in the technical area that's got the whole city buzzing.
Jose Mourinho up against Pep Guardiola.
These two have clashed before. Verbally at least.
So what have they had to say about their first Mancunian match-up? First up is Pep Guardiola:
And what does Jose Mourinho have to say?
Manchester United manager Jose Mourinho has played down any talk of a rivalry between himself and Manchester City manager Pep Guardiola.
Both men have enjoyed 100 per cent starts to life at clubs they joined in the summer, but something has to give when the duo resume hostilities after going up against one another at Real Madrid and Barcelona.
The Portuguese was respectful, if reluctant to talk at length, about Guardiola, calling him a "very good manager" as he focused his attention elsewhere.
Former Manchester United forward Andy Cole says the the players are more important than the managers when it comes to the Manchester derby.
It's United against City and Jose Mourinho versus Pep Guardiola when the two clubs meet at Old Trafford in the Premier League on Saturday.
Meanwhile ex-Manchester City player Trevor Sinclair hopes Mourinho behaves on the touchline and lets the football make the headlines.
Manchester United frontman Zlatan Ibrahimovic has sent a warning to Manchester City's new goalkeeper Claudio Bravo ahead of the derby on Saturday.
The Swedish striker posted a video on social media showing him sending a parcel to Bravo ahead of the Premier League showdown at Old Trafford between the rival clubs.
In a message he says, 'Welcome to Manchester! Here's some training gear, you're gonna need it. See you Saturday.'
Since joining on a free in the summer, Ibrahimovic has scored four goals in his opening four games with United.
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