Stephen O'Brien is set to step down after serving as Eddisbury's MP for 15 years.
Mr O'Brien was first elected in the July by-election of 1999.
He has confirmed that he will not seek re-election on the 7th of May and will be taking on a new job at the United Nations in New York, as the next Under-Secretary General for Humanitarian Affairs.
The Eddisbury Conservative Association will now start the selection of the Conservative Party Candidate for Eddisbury for the General Election.
The funeral of the MP Paul Goggins takes place at St John's, Salford at midday. It is a public service.
The funeral of the MP Paul Goggins takes place in Salford at midday today. He was taken ill suddenly when he was out running. His family have asked for no flowers but for people to donate to one of three charities- Cafod, The Cardinal Hulme Centre and Leukaemia Lymphoma Research.
A dad says the government's back to work schemes have put his vulnerable daughter in hospital.
Sheila Holt from Rochdale has a psychiatric condition.
Her family say the Department of Work and Pensions said it shouldn't stop her working.
Daniel Hewitt reports.
A GP who has failed in a bid to get MPs to debate his e-petition says he is angry at being ignored.
Dr Kailish Chand wanted the Health and Social Care Bill dropped. His petition collected more than 160,000 signatures.
He says he is "disappointed, saddened and angry".
Ashton-Under-Lyne based Dr Kailash Chand OBE passed the 100,000 signatures mark making it eligible to be debated in the House of Commons. He and Stalybride and Hyde MP Jonathan Reynolds will put the petition before the backbench business committee and request a debate.
This could mean the Government discussing dropping the bill before the bill itself is even put before Parliament. Dr Chand will be informed before the end of the day as to whether his E-Petition has been successful.
Calls for the government to drop controversial health reforms could force a parliamentary debate. Dr Kailash Chand OBE from Ashton-under-Lyne has gathered massive support after launching an e-petition.
The future of the government's NHS bill could be debated in parliament, after an e-petition was set up by Ashton-Under-Lyne GP Kailash Chand. A decision is expected today, after the petition gained over a 160,000 thousand signatures, making it one of the biggest e-petitions ever.
Kailash Chand from Ashton-Under-Lyne wants the Government to drop the Bill.
His e-petition has had one of the biggest ever responses.
Usually e-petitions only need 100,000 backers to be considered for a debate - but his has surpassed that by 60,000.
A decision on a possible debate is expected today.