Wigan Warriors set off for Wembley this lunchtime ahead of Saturday's Tetley's Challenge Cup Final against Hull.
Hundreds of fans are expected at the DW Stadium to cheer them on their way.
The club's suggesting they arrive from 11.15am onwards.
There will be a segregated area on the West Stand side of the stadium from where fans will have the opportunity to wish the team well.
Head coach Shaun Wane said: "It would be great to see as many fans as possible at the Stadium on Thursday to give this group of players a massive send off for the Final.
"We had a great reception a couple of years ago before leaving for the Cup Final with what seemed like thousands of supporters there to wish us well.
"I would like to thank all of our fans for the way they have got behind us all season and look forward to seeing them all down at Wembley."
Police have released pictures of ten people they'd like to speak to following fighting among Millwall supporters at last weekend's FA Cup semi-final at Wembley. Violence broke out during the game between Milwall and Wigan. 11 people were arrested at the time.
Police said they are investigating incidents involving Millwall supporters at today's FA Cup semi-final that left some fans bloodied and younger ones in tears.
A Scotland Yard spokesman said:
Ten football fans were arrested after fighting broke out in the Millwall supporters' area during the south London club's defeat to Wigan in the FA Cup semi-final at Wembley, the Metropolitan Police said tonight.
Millwall football fans fought each other at Wembley as their side lost 2-0 to Wigan in the FA Cup semi-final today.
Police intervened after MIllwall fans fought each other in the stands at Wembley as the London club lost 2-0 to Wigan Athletic in the FA Cup semi-final.
Crewe manager Steve Davis says their remarkable season has exceeded all expectations.
Blackpool manager Ian Holloway insists he's proud of his players despite them losing in the Championship play off final.
The Tangerine Army will have had a long journey home after seeing their side beaten 2-1 at Wembley by West Ham.
The defeat means the club miss out on making an immediate return to the Premier League.