Rosie McLoughlin died aged just 14 on Saturday after a long battle with the brain disorder Rett Syndrome.
Coleen returned home early from her holiday to Barbados to be at her sister's side. She said "We are absolutely heartbroken to have lost our angel." Sarah Rogers reports.
For more information go to the Rett Syndrome Research Trust UK website.
You can also find out about the work of Claire House Hospice at www.claire-house.org.uk.
More top news
Staying unsettled and cool but a slow improvement from midweek until Friday
Warrington coach Tony Smith has effectively ruled Matty Russell out for the season with a second major ankle injury in four months.
The jury in the trial of three men accused of murdering off-duty policeman Neil Doyle has retired to consider its verdicts.