The second video in our series on organ donation as part of ITV's From the Heart campaign.
We're looking at why there is such a shortage of people on the organ donor register.
Last year we followed the story of Natalie Kerr. She underwent a double lung transplant at Wythenshawe Hospital.
One year on, she has gone back to talk to those who saved her life, and to urge others to sign up.
We've been given extraordinary access to a transplant at Manchester Royal Infirmary, which has the UK's busiest renal transplant programme
Catch up on our series to mark ITV's From the Heart campaign in the North West
Our reporter Mel Barham meets Ron Burrows from Southport, whose wife Philomena died on the transplant waiting list.