Greater Manchester Fire service say the blaze at the former Turner and Newall asbestos factory in Rochdale is now under control.
Up to 50 fire fighters have been at scene since the early hours.
Nearby residents were told to keep all windows and doors shut as a precaution.
More top news
The family of a man reported missing have paid tribute to him after his body was discovered in a field near Beech Tree Lane in Lymm.
A couple from Levenshulme who lived a lavish lifestyle funded by money laundered from a drug empire have been jailed.
Slow improvement to drier yet colder conditions as we head closer towards the weekend