Almost half of all children in Manchester Central are living in poverty. The area has the highest number of youngsters living below the breadline anywhere in the country.
Children's charity Barnados says urgent change is needed to ensure young people get the best start in life. Manchester Central MP Lucy Powell says the changing face of the city may explain the statistics.
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Stephen Jones described how he rushed to help severely wounded children in the aftermath of the Manchester Arena bomb attack.
Saffie Roussos, believed to be eight years old, was described as a "beautiful little girl".
At least six people from the region are missing after the terror attack at the Ariana Grande concert in Manchester on Monday.