Firefighters from Cheshire and Greater Manchester have been battling a blaze at a Cheshire bar-restaurant Panacea.
They were called there at around 10.30pm on Tuesday evening.
Several pictures of the fire have appeared on Twitter.
Rumour is panacea is on fire? http://t.co/qHoNTYTPvK
Rip panacea! http://t.co/USItE10Tuv
The blaze broke into the roof space and as of 5am on Wednesday, crews were still at the scene fighting the flames.
Cheshire fire service say crews wearing breathing gear were at the scene and were trying to stop the fire spreading to nearby buildings.
Cheshire police say no-one was reported to be inside the building at the time.
The Manchester Evening News is reporting that the venue, which is popular showbiz hangout, was going through a £3.2m refurbishment. It was also the scene of a previous fire in 2008, the newspaper's website says.