Hundreds of jobs are at risk as pharmaceutical giant AstraZeneca announced cuts.
The company, which has a plant in Macclesfield, want to cut 700 jobs from the UK over the next three years.
More top news
Ex-Manchester United captain Rio Ferdinand has tipped his old club to finish in the top three of the Premier League.
The Met Office says there will be rain and snow for many parts of our region over the next few days.
A couple killed in a collision on one of Manchester's busiest roads have been named.