Firefighters are tackling a blaze at a derelict building in Manchester's Northern Quarter/
Fire crews were called at around 6pm to the building on Warwick Street/Oldham Street.
People in the area are being asked to keep their doors and windows shut.
More top news
Two people are under arrest and a murder investigation has been launched after the death of a newborn baby.
The 72-year-old had to be helicoptered from the mountain, when he was just a few hours from the summit on Monday.
Honda Racing has confirmed John McGuinness and Guy Martin will be teaming up for the Isle of Man TT this June.