Manchester City have close to a full squad available, with winger Scott Sinclair the only notable absentee after surgery to remove a blood clot from his shoulder.
Midfielder Yaya Toure is fit after recent concerns about fatigue and playmaker David Silva (hamstring) is back in contention. Back-up goalkeeper Costel Pantilimon, who has played in all the previous rounds, is expected to be selected ahead of England number one Joe Hart.
Wigan boss Roberto Martinez must decide whether to stick with his wobbly defence. Antolin Alcaraz is rated no more than a 50-50 chance, while captain Gary Caldwell is most at risk following his mistake against Swansea on Tuesday and Roger Espinoza looked ill at ease in the left wing-back role.
Ali Al Habsi is expected to return at the expense of on-loan Joel Robles in goal, as he did for the semi-final win over Millwall.
Top scorers: Carlos Tevez (Man City) 17; Arouna Kone (Wigan) 13
Match odds: H 1-3 A 8-1 D 4-1
Referee: Andre Marriner (W Midlands)