Matthew Finnegan, chair of the Save Trafford General campaign, said: "It is tearing the heart out of the hospital - the birthplace of the NHS - and that means that the hospital's future is in real danger.
"It will mean that patients will have to travel further and wait longer for treatment.
"These decisions can't just be made by clinicians - they have got to listen to what local people say. And people want an A&E, it's not an unreasonable request.
"Local people will be appalled and disgusted that they have not been listened to."
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Showers or longer spells of rain. Severe gales on Sunday with storm force winds for coasts and hills
Tyson Fury plans to give his fans a song when he's finished with world heavyweight champion Wladimir Klitschko on Saturday night.
Often very windy, especially as we head into Sunday, with rain or showers. Met Office 'Be Aware' warnings have been issued