Group Manager for Greater Manchester Fire and Rescue Service, Andy Heywood said: "At the moment we are applying water to the outside of the building to stop the fire spreading.
"By allowing the fire to burn inside the building it stays hot and gives off smoke which is relatively clean.
"Unfortunately because the building and fire is right next to the railway line we have asked for the trains to be stopped and overhead line equipment isolated.
"It could be several hours before we can be confident of what will happen to the building and how the fire will develop."
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A passenger plane aborted a landing just yards off the runway at Manchester Airport in extreme winds and heavy rain.
Wet and cloudy for most with some clearer spells later. A cold start to the night but further rain and strong winds into Tuesday
Has your area been affected by the storm? Here are some photos from across the region.