Newly-promoted Burnley will face a tough test on their return to the Premier League, as they take on Chelsea at Turf Moor.
Defending champions Manchester City open the season away at Newcastle United.
The North West teams' opening matches are:
Burnley v Chelsea
Leicester City v Everton
Liverpool v Southampton
Manchester United v Swansea City
Newcastle United v Manchester City
More top news
Political leaders will go head-to-head at ITV's studios in MediaCityUK in Salford, ITV has confirmed, as the set for the event is unveiled.
Relatives of some of those who died at Hillsborough have told a court that police asked them about alcohol moments after identifying bodies.
ITV have confirmed that The ITV Leaders’ Debate will be held at studios in MediaCityUK in Salford.