Newly-promoted Burnley will face a tough test on their return to the Premier League, as they take on Chelsea at Turf Moor.
Defending champions Manchester City open the season away at Newcastle United.
The North West teams' opening matches are:
Burnley v Chelsea
Leicester City v Everton
Liverpool v Southampton
Manchester United v Swansea City
Newcastle United v Manchester City
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Burnley manager Sean Dyche has confirmed he is in talks with Joey Barton about bringing the free-agent midfielder to Turf Moor.
David Beckham and Sir Alex Ferguson joined mourners today at the funeral of Neville Neville, the father of ex-footballers Gary and Phil.
The 52-year-old contacted the dead soldier's family and claimed the murder was a conspiracy.