Newly-promoted Burnley will face a tough test on their return to the Premier League, as they take on Chelsea at Turf Moor.
Defending champions Manchester City open the season away at Newcastle United.
The North West teams' opening matches are:
Burnley v Chelsea
Leicester City v Everton
Liverpool v Southampton
Manchester United v Swansea City
Newcastle United v Manchester City
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Schoolboy Tommie Rose, the boy who's made £14k selling sweets in the playground has turned his hand to to online business world.
Chilly start, some frost in places, especially out in the countryside. Fine and bright today, best temperatures in the Isle of Man
Cold tonight with a ground frost in rural spots. Some mist forming. Chilly start on Monday, sunny spells and cloud