Newly-promoted Burnley will face a tough test on their return to the Premier League, as they take on Chelsea at Turf Moor.
Defending champions Manchester City open the season away at Newcastle United.
The North West teams' opening matches are:
Burnley v Chelsea
Leicester City v Everton
Liverpool v Southampton
Manchester United v Swansea City
Newcastle United v Manchester City
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An investigation is underway after a man died following a fight in Ancoats. A 62-year old man is being questioned on suspicion of murder.
Coldplay used their headline performance at Glastonbury to pay tribute to Warrington band Viola Beach.
Major changes to the Metrolink service have come into effect. Trams wont stop at St Peter's square or travel to Eccles until the end of Aug.