Newly-promoted Burnley will face a tough test on their return to the Premier League, as they take on Chelsea at Turf Moor.
Defending champions Manchester City open the season away at Newcastle United.
The North West teams' opening matches are:
Burnley v Chelsea
Leicester City v Everton
Liverpool v Southampton
Manchester United v Swansea City
Newcastle United v Manchester City
More top news
Feeling fresher into Sunday but staying dry with some hazy sunshine. Kerrie has the detail......
Drier and brighter into Sunday after a cooler night
Mild but rather cloudy. Gusty winds for coasts and hills