Police are advising motorists to avoid the A538 Hale Road after a crash.
A statement from Greater Manchester Police said:
"GMP is advising that motorists avoid the A538 Hale Road following a serious RTC.
Hale Road is closed both ways at the junction with Brooks Drive and is likely to remain so until at least 1pm.
Motorists, especially those hoping to travel to the airport, are advised to avoid the area if at all possible."
The aftermath of the crash was captured by Ellis Ashely onTwitter.
More top news
Former Liverpool and Newcastle defender Jose Enrique has revealed he has had surgery to remove a rare brain tumour and is now in recovery.
The mother-of-two said she was told by RSPCA investigators they were looking at the possibility that poison-laced sausages were involved.
The Beatle made several stops during his trip through Liverpool with James Corden and shocked many Scousers along the way.