Road closures in place around Sackville Street and the surrounding area have now been lifted.
Police evacuated buildings on Sackville Street after an explosive chemical was found at a University of Manchester Institute of Science and Industry building.
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Emergency services attended and a man, believed to be in his 40s, was found dead at the scene.
Bright and warm on Sunday with a muggy night to follow
According to police, the building involved is derelict, but was once used as a hostel.