Boris Johnson has been beaten by one of his deputies in the race to find a safe Parliamentary seat.
Kit Malthouse, Deputy Mayor for Business and Enterprise, has been chosen as the Conservative candidate in North West Hampshire.
Mr Malthouse, a member of the London Assembly, will be defending a Tory majority of 18,500 in next year's general election.
Boris Johnson is widely expected to to stand for Parliament in the same election although he has yet to publicly confirm his ambition to become an MP for the second time.
The Mayor's official spokesman said:
The Mayor is delighted at Kit Malthouse's selection as the Conservative candidate for North West Hampshire.
Over the course of the last six years, Kit has driven the Mayor's agenda on policing and crime and, more recently, on business and enterprise, with enormous success.
The Mayor believes he will be an excellent MP for the people of North West Hampshire.