"We appreciate that people are going to hold passionate views about changes to their local NHS services. Local healthcare organisations, doctors, nurses and other health professionals, with their knowledge of the patients they serve, are best placed to decide what services they need for patients in their area.
"We have always been clear that the NHS must be open about any plans and changes must show a clear benefit to patients."
The NHS's North West London trust has recommended four A&E departments be closed.
The units in Ealing, Central Middlesex, Charing Cross and Hammersmith could be downgraded to 24/7 urgent care centres.
The new proposed plans would see other major hospitals take A&E patients, peforming both emergency and elective operations, as well as running tensive care units, psychiatric liaison, inpatient paediatrics and a maternity unit.
The hospitals tasked with taking on the extra burden are Chelsea and Westminster, Hillingdon, Northwick Park, St Mary's and West Middlesex.
A week of campaigns by the medical profession start today. They are protesting against proposed NHS cuts. Dr Louise Irvine from the Lewisham Hospital Campaign says by doing this they are taking the NHS down a one way road to privatisation.
A week of protests against hospital reform plans starts today. Defend London's NHS week will see a coalition of doctors, patients and health workers against plans to downgrade A&Es and other vital hospital services in the capital.
The campaign kicks ogg with a press conference at the House of Commons bringing together representatives of the Lewisham, Ealing, Hammersmith & Fulham, Kingston and Islington hospitals campaigns.