Arsene Wenger says his side is showing few signs of fatigue as they embark on a run of fixtures which will test their hopes of progressing both in Europe and in the Barclays Premier League.
The Gunners are already three points clear at the top of Champions League Group F when they take on Napoli. A draw would be good enough to secure first place and with it seeding for the knockout stage.
The players will have little time to recover when they travel back from Italy directly after the Napoli match before tackling Manchester City at the Etihad Stadium on Saturday lunchtime. Arsenal then go into a showdown with Chelsea on December 23.
There is then the north London derby against Tottenham in the FA Cup third round on January 4.