Crystal Palace secured their place in next season's Premiership with a 1-0 win over East London rivals, West Ham. The only goal of the game was a penalty scored by The Eagles' Mile Jedinak.
Relegation strugglers, Fulham failed to make it three wins in a row after losing 3-1 to Spurs at White Hart Lane. Paulinho opened up the scoreline, then Fulham's Steve Sidwell equalised. Goals then followed from England under 21 striker, Harry Kane and defender, Younes Kaboul.
Fulham will take on Spurs later this afternoon. The West Londoners are making great strides in their relegation battle, having won their last two games. On loan midfielder, Lewis Holtby is ineligible to play in this match.
However, Mousa Dembele, may be included in Tottenham's starting line up against his old team, after recovering from a hip injury.
Tottenham Hotspur manager Tim Sherwood has questioned whether London derbies are as significant anymore as a result of the influx of foreign players into the Premier League.
Sherwood was speaking ahead of his side's Premier League game against strugglers Fulham on Saturday.
Asked whether London derbies were as significant anymore, Sherwood replied: "Probably not because there are not so many guys from the area and not a lot from England but it's still a game and it's a game in the Premier League and one they should be up for.
"But does it mean anymore? Probably not but it is certainly important to me and the next four games are crucial," Sherwood added.
Fulham are preparing for a crucial London derby against Tottenham on Saturday as they continue their bid to avoid relegation.
Buoyed by successive victories against Aston Villa and Norwich, Fulham are now just two points adrift of safety with four games remaining.
Fulham manager Felix Magath revealed that he had been consulting Lewis Holtby -who is on loan from Spurs - for advice ahead of the clash.
"Sure I ask Lewis how he sees the situation, how a certain player is, but it is not the only one kind of information I will get. I try to get all the information I can get," Magath said.
Chelsea hope to keep pace with Premier League leaders Liverpool when they play Sunderland, while West Ham take on Crystal Palace in the second of this weekend's London derbies.