- 7 updates
The 43 Tesco stores facing closure have not yet been made public but a "significant proportion" will be Tesco Express convenience stores at sites across the country.
New chief executive Dave Lewis has not yet indicated the scale of the job losses at the beleaguered supermarket, with full details set to be known by April.
Employees affected by the closures will be informed over "coming months".
Head office jobs will also see cuts as Tesco cuts overheads by 30%.
Mr Lewis said he understood how the announcement would hit "hard-working people", adding: "I am not immune to the impact of the decisions we have had to take on our colleagues."
The 43 unprofitable Tesco stores facing closure are "mostly" Express outlets, the retailer told ITV News.
The supermarket said it would be consulting with store employees affected by the closures "over the coming weeks".
Tesco's new chief executive Dave Lewis acknowledged that the supermarket has "some very difficult changes to make" as it unveiled new measures in a bid to reduce its capital expenditure and cut costs by £250 million a year.
Beleaguered supermarket Tesco has unveiled a raft of measures it hopes will turn around its fortunes.
With the company's pension deficit and debt levels growing, Tesco said it would reduce its capital expenditure for next year to £1 billion, from no more than £2.1 billion this year and cut costs by £250 million a year.
Tesco's money-saving plans include:
- Closing 43 unprofitable stores
- Closing it final salary pension scheme
- Shutting its main headquarters in Cheshunt, Hertfordshire, in 2016, moving to Welwyn Garden City
- Restructuring central overheads to save an estimated £250 million a year
- A "significant revision" to its store-building programme - with plans for 49 new stores scrapped
- Selling off Tesco Broadband and UK download business Blinkbox to TalkTalk
- Exploring options to sell its Dunnhumby data business, as well as cancelling a final-year dividend for 2014/15
Unveiling a raft of measures, Tesco announced the appointment of Halfords Chief Executive Matt Davies as the new boss of its UK and Ireland business.
The supermarket's new CEO Dave Lewis described him as "an experienced retailer with a proven track record of turning around businesses".
He will take up the position on June 1.
Latest ITV News reports
The supermarket giant is also planning to axe more than 40 loss-making stores as part of a £250m cuts agenda.
The under-pressure supermarket is trying to regain market share by cutting prices on big brands such as Coca-Cola, Hovis and Marmite.