People inside escaped before fire crews arrived and no one else is thought to be involved in the fire at this stage.
Enfield's High Street is closed to traffic and people living in the area are being warned to keep doors and windows closed as a precaution against the heavy smoke. Firefighters are expected to be at the scene for some time this morning.
The fire is affecting a range of shops, including a restaurant, as well as a number of flats above them.
Our firefighters are working extremely hard in very challenging conditions to stop this fire from spreading and have managed to contain the fire to two units in the row of shops involved.
Twelve people have escaped from a burning building after a large fire broke out in a restaurant and nearby flats in north London. More than 70 firefighters were called to the High Street in Ponders End in Enfield at around 1:30am.
Ukip council candidate William Henwood has resigned his membership of the party following a controversy over offensive comments about comedian Lenny Henry.
A Ukip spokesman said that any breach of party rules would be investigated, but also criticised the exposure of candidate William Henwood's tweet by "the other parties."
A spokesman for the party told the BBC:
Any breach of our rules will be duly investigated and action will be taken.
However one has to question why the other parties are spending hours behaving like secret police and trawling through the social media of Ukip candidates who are everyday men and women, rather than actually doing politics.
Perhaps if they did they would be better able to tackle us on policy, rather than having to rely on smear campaigns to try to undermine Ukip's increasing popularity.
Were we to return the favour we would find an even greater wealth of embarrassment and disgrace in the other three parties' ranks to also spread across the media.
Ukip is facing a fresh backlash over comments made on Twitter by one of its candidates who suggested Lenny Henry should emigrate to a "black country" in response to a speech by the actor and comedian that said ethnic minorities were under-represented on British television.
William Henwood, who is standing in a council election, told the BBC: "I think if black people come to this country and don't like mixing with white people why are they here? If he (Henry) wants a lot of blacks around go and live in a black country."
An 11-year-old boy, who went missing from Enfield yesterday, has been found.
Nasco Chageedera disappeared around midday on Saturday after setting off towards the adventure playground on Fore Street.
A top student facing deportation has told Daybreak she is "really frightened" she will be forced to return to Mauritius, and fears her life will be in danger if she is forced to leave the UK.
Speaking from Yarl's Wood detention centre, Yashika Bageerathi, said Mauritius was "no longer the paradise island that it used to be".
Campaigners and fellow students of Yashika Bageertathi protested outside the Home Office in London on Sunday.
An A level student who fled her home in Mauritius after a family member threatened her with violence and sexual assault has spoken of her fears if she returns.
Yashika Bageerathi said the man in question, who deals drugs, had people waiting for her to arrive home and was angry because he had lost money.
My family will know where I am. He [the family member] is already after our lives, he says he has people waiting at the airport for us to come back.
He lost a lot of money because of us to do with his drug-dealing.