Police have issued CCTV images of a man and two younger women they are trying trace following the attacks.
In a statement, the Met Police said: "In the first incident, at approximately 0400hrs, the substance was sprayed at two men outside the Lightbox nightclub in South Lambeth Place, Vauxhall. This followed a verbal exchange between the two men and a group outside the venue.
"Following comments made during the exchange, this incident is being treated as a homophobic hate crime."A short time later, police were made aware of a third man who had also been sprayed in the face with a substance in the vicinity of the nightclub.
Three have been sprayed in the face with bleach outside a nightclub in Vauxhall in what police are treating as a homophobic hate crime. The attacks happened outside the Lightbox club at around 4am Sunday morning.
In the first attack, two men were sprayed with a substance - thought to be ammonia. A third man was attacked a short time later.
A cyclist has been killed in Vauxhall, south London, following a collision with a lorry this morning.
The cyclist, believed to be 52-years-old, died at around 7am this morning in Parry Street after colliding with a tipper truck.
A Twitter user posted a picture seemingly showing police at the scene of the crash.
Cyclist killed by a tipper truck at Vauxhall Cross this morning. Desperately sad. http://t.co/ldUGL77gyE
Police are appealing for information and witnesses following the incident. If you witnessed the event contact police on 101 or call Crimestoppers anonymously on 0800 555 111.
A painting by renowned artist Sergei Chepik has been stolen from an office in Vauxhall.
The work called 'Night Flight' was taken from the office at Westminster Business Square on Durham Street. It was not on display, but kept in a silver art bag and leaning against a wall when it was stolen.
Detective Constable Anne Hogarth, said: "The painting had been on display at the Catto Gallery in Hampstead in February in a retrospective exhibition of the artist's work and had been temporarily stored in the business premises and was to be returned to the owner's home when it was stolen."
Hundreds of people including MP Kate Hooey, have backed a campaign supporting saving the Vauxhall Bridge bus station, amid fear that it could be demolished to make the area more cyclist and pedestrian-friendly.
Lambeth Council and Transport for London (TfL) is due to launch a consultation later this year on the future of the Vauxhall Cross gyratory. Ms Hooey said: "The bus station is popular and needed [...] and not negotiable".
According to the Evening Standard, leader of Lambeth Council Lib Peck, said: “We know there is strong opinion in the local community who will have the opportunity to comment, and we are clear that any new scheme has to work for buses.”
Today marks one year since a helicopter crashed into St George's Wharf Tower in Vauxhall. The pilot, Captain Pete Barnes, and a pedestrian, Matthew Wood, were killed.
The Civil Aviation Authority said it was the first fatal helicopter crash in central London since records began in 1976.
Five people were taken to hospital and seven more were treated at the scene. The Air Accidents Investigation Branch began an enquiry shortly after the crash which has yet to report.
After years of campaigning, South Londoners are getting the tube extension they've been hoping for.
The Government is expected to announce that a one billion pound extension to the Northern Line has been given the go-ahead today.
The Northern Line Extension will create two new tube stops in Battersea: one near Wandsworth Road and another next to Battersea Power Station.
It forms wider plans to regenerate Vauxhall and Battersea that also sees news homes and commercial buildings being proposed along the riverfront as well as the new American embassy being built in the area.
This morning another accident left a cyclist injured after colliding with a bus. The incident in Vauxhall came as figures were released showing the number of buses involved in serious accidents in the capital. Over the last five years 1,889 people have been killed or seriously injured.
Ria Chatterjee reports.
At around 08:10 this morning (Wednesday 13 November) a route 360 single deck bus, operated by Go Ahead, was involved in a collision with a cyclist on Vauxhall Bridge, SW1.
Our priority is of course the wellbeing of the cyclist and we are aware that the ambulance service attended the scene.
As is normal in an incident of this nature, there will be a thorough investigation to establish the circumstances.
The Mayor's Roads Task Force report aims to ensure the capital can cope with major population growth, support jobs and thousands of new homes in the coming years.
The ambitious £30 billion road improvement plan for London was produced by a task force set up by Mayor Boris Johnson.
The 20-year vision includes improvement to the North and South Circular roads, new "flyunders" and major schemes at Vauxhall, Waterloo, Elephant and Castle and Old Street.
There are also plans for improved bus services, more 20 mph zones, and proposals to improve cycling and walking.