Campaigners fighting to save a children's heart surgery unit have been left disappointed after the Court of Appeal ruled that consultations which proposed its closure were lawful.
Bosses at the Royal Brompton in Chelsea now fear that, if the current plans are approved, the future of the entire hospital could be under threat.
But those involved in the planning say no final decision has yet been made.
Liz Wickham has sent this report.
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Wealthy businessman Ivan Massow wants to succeed Boris Johnson at City Hall in 2016.