Around 70 firefighters are tackling a blaze at a factory in Greenwich.
The fire at the premises in Peterboat Close is being battled by 12 crews.
They were called to the scene, off the approach to the Blackwall Tunnel, shortly before 3.30am.
More top news
Tube bosses have made a new offer to drivers - to try to break the deadlock over the launch of the new Night Tube service
In an interview with ITV News, the Mayor said his 'sympathies were with the PKK' - a proscribed Kurdish terror group
Martin Stew has the forecast: