Around 70 firefighters are tackling a blaze at a factory in Greenwich.
The fire at the premises in Peterboat Close is being battled by 12 crews.
They were called to the scene, off the approach to the Blackwall Tunnel, shortly before 3.30am.
More top news
The London property market is expected to be the hardest hit as buyers sit it out to see how the economy will be affected.
The former London mayor paid tribute to David Cameron just hours after the Prime Minister announced his resignation.
The pound crashed to its lowest level in 30 years as Britain voted to leave the EU.