Around 70 firefighters are tackling a blaze at a factory in Greenwich.
The fire at the premises in Peterboat Close is being battled by 12 crews.
They were called to the scene, off the approach to the Blackwall Tunnel, shortly before 3.30am.
More top news
West Ham have opened an investigation into a flyer that was allegedly distributed ahead of the game with Chelsea.
Damon Joseph Smith smiled and waved at his mother, who waved back.
Tanguy Marie De Carne, 53, jumped red traffic lights and rode on busy pavements through the City pursued by police