The Royal Brompton Hospital has lost the battle to save its children heart surgery unit.
The pioneering hopsital in Chelsea has been warned that such services will now be concentrated at two other hospitals - Great Ormond Street and the Evelina.
The defeat is the end of a long campaign, which was fought all the way to the Court of Appeal by campaigners hoping to save it.
More top news
Arnis Zalkalns, a 41-year-old Latvian builder, vanished a week after 14-year-old Alice went missing from her home at Hanwell.
The 14-year-old vanished near her home in west London exactly three weeks ago.
A Labour MP tipped as a possible candidate for London mayor has admitted crashing into a motorcylist her second accident in just over a year