A man aged 54 suffering burns was taken to a south London hospital where his condition is understood to be critical after the fire in Streatham.
Police inquiries are underway after two bodies were found at the scene of the fire, on waste ground at Streatham High Road SW16, near the junction with Lewin Road.
Police were called to the scene at around 2.30am this morning.
London Fire Brigade extinguished the fire.
The Met say post-mortems will be scheduled in due course.
More top news
If you are black and a Londoner new figures reveal you are three times more likely to be Tasered by police.
Cloudy with scattered showers for the rest of the week.
Figures show an increasing trend for barriers to be left open, potentially making life easy for fare dodgers.