The attack on Tottenham supporters happened at Rome's Drunken Ship pub.
Bar co-owner Gabriele Cianella said the attackers had thrown pieces of iron at the windows and were wearing knuckle dusters.
I think this is the first time that something so bad has happened. We have had other incidents like this but this is the worst.
If you throw stones and knuckle dusters I think you want to hurt someone. There was a lot of blood inside on the floor.
Now we also have some blood on the windows. They came here to hurt someone.
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Noye, now 69, was convicted of murder in April 2000 and sentenced to life with a minimum term of 16 years.
Trevor Timon, 31, had a history of violence before the unprovoked attack on the 30-year-old in Blackheath, south-east London last August.