A series of live concerts are set to be held at the Olympic Stadium this summer.
Wireless Festival and Hard Rock Calling, previously held in London's Hyde Park,have been scheduled for July ahead of the full opening of the Olympic Park in Stratford in spring next year.
Music promoter Live Nation has won exclusive rights to host major music concerts in the North Park and stadium. It is the inaugural contract for Queen Elizabeth Olympic Park.
John Reid, president of concerts at Live Nation Europe, said: "In the coming weeks, we will unveil the headline acts for the first Wireless and Hard Rock festivals to be staged in London's new flagship venue, which promise to be the UK's blockbuster events of 2013."
The events will form part of a summer series on the park, to include RideLondon - a festival of cycling and road races along with a weekend of music, sport and culture to celebrate the park beginning to re-open.
London mayor Boris Johnson said:
"Our vision for Queen Elizabeth Olympic Park has always been as a destination for world-class sport, as well as for major cultural and leisure events and last summer the world saw what an amazing venue we have created with our iconic stadium, sports facilities and new parklands.
The confidence now shown by one of the world's leading live entertainment promoters to relocate two of its biggest music festivals from the centre of the capital is a ringing endorsement of our legacy plans.
Along with the other major international sports events we have already secured, this latest news proves that the park has a very bright future indeed."
More top news
Two men have been taken to hospital after a "suspected acid attack" in east London.
Mr Gard and Miss Yates want to spend the final hours with their son at home in Bedfont, west London.
A ninth penguin was injured.