Two people die every week while waiting for a transplant in and around London. Right now, there are 2,000 people on the transplant waiting list.
As part of ITV's From The Heart campaign, Our reporter Ria Chatterjee went to meet one of those waiting for a transplant, 17-year-old Sophie Washington.
Vincenzo has been transformed from a patient so sick he could not wash his face to a man who strides confidently with a gleam in his eye.
Alex Smith was diagnosed with a heart problem but after receiving a transplant he feels he has been given the "greatest gift of life."
While 90% of people believe donating an organ is the right thing to do - only 30% are signed up to the organ donor register.