Natalie's mother Angie Smith said: "She was bubbly, intelligent, a normal girl...used to love her friends. She's loyal and she had a great job, great life and now she can't go out on her own.
"She can't bath alone. She needs somebody to be with her all the time. She's on so many drugs that she has hardly any memory.
"She cannot read properly. She can't write, can't sign her own name, can't fill in a form, due to the amount of drugs that she's on."
Natalie's father Derick Smith added: "She's also deteriorating. The worst case scenario we've had is 10 days in a medically induced coma."
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A woman and man have been charged with murder after a baby was found unresponsive on a bus.
Rebecca Casserly was on her way to buy a coffee in north London when her phone was suddenly snatch from her hand by a man riding a bike.
Lee Curley took more than 120 pictures and videos of his attacks on the girl, said to be under the age of 13.