Natalie's mother Angie Smith said: "She was bubbly, intelligent, a normal girl...used to love her friends. She's loyal and she had a great job, great life and now she can't go out on her own.
"She can't bath alone. She needs somebody to be with her all the time. She's on so many drugs that she has hardly any memory.
"She cannot read properly. She can't write, can't sign her own name, can't fill in a form, due to the amount of drugs that she's on."
Natalie's father Derick Smith added: "She's also deteriorating. The worst case scenario we've had is 10 days in a medically induced coma."
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Officers say the child, aged two, was targeted in the Lewisham Shopping Centre.