Network Rail says a derailment early this morning at Camden Road has caused extensive damage to overhead wires. It means services will not be run between Stratford and Gospel Oak until further notice. Early indications show that the line is expected to remain closed for a number of days.
In a statement, Network Rail said: "Over the coming days Network Rail engineers will be working tirelessly to reopen the railway as quickly as possible. This work will involve large pieces of plant and equipment, including a very large road crane.
"We will be keeping the local community and passengers up to date with the situation as our work progresses."
More top news
Research into property prices has found London has more areas with an average price of more than £1m than anywhere else in the UK.
A permanent memorial will be unveiled today in memory of murdered Middleton soldier Lee Rigby.
The desk and chair where Charles Dickens sat to write his final novels have been bought for the nation using a national heritage grant.