Blake, a 25-1 outsider to win, is a Goldsmiths College music graduate who was previously nominated for the Mercury for his self-titled debut album which he recorded at his home in New Cross, south east London.
Accepting his award, he said it was "amazing" to be in the running for an award with chart veteran David Bowie.
Asked what he would spend the money on, he said: "I'll make sure it goes to some good use".
He added: "This is the first award I've ever won apart from a tennis trophy which I won when I was about 12-years-old at my school and I'll hold them in equal esteem".
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Hundreds of passengers were ordered to leave the terminal building and flights grounded after passengers suffered difficulties breathing.
Council leaders today called on the government to provide extra money to help resettle the youngsters in the capital.
An eyewitness said: "It was very unnerving. It was just after 12pm and there were suddenly police vans and cars everywhere."