Police are appealing for witnesses after an incident involving a 205-route bus, in which a cyclist, believed to be in his 30s, was killed.
He was not wearing a helmet at the time of the collision, police added.
The victim, who has not yet been identified, was taken to an east London hospital. Police added there had been no arrests and inquiries continued.
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Scotland Yard said two murder investigations have been launched following the separate incidents, which both happened in the past week.
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The Met Police says 143 firearms have been handed in at stations across the capital in just seven days, including two antique machine guns.