A judge rejected the councils' claim that the mayor's plans to close 10 fire stations were legally flawed for a number of reasons, including a failure to take into account the reality of increased fire risks in inner London.
Campaigners say the cuts, which involve the loss of more than 500 jobs and the axing of 14 engines, would be "reckless, wrong and will seriously endanger lives".
But Mr Justice Foskett ruled the process by which the closure decision was reached was lawful.
He said: "I appreciate that the outcome will come as a disappointment to a number of people who had hoped to see the proposed changes to the provision of fire services in their area set aside."
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The family of a father-of-three from East Ham have made a fresh appeal to catch his killer 20 years after he was murdered.
The Metropolitan Police has paid £45,000 in damages in an out-of-court settlement following the 'unlawful arrest' of a black motorist.
John Cantlie, who worked for a number of Fleet Street newspapers, is thought to have been taken hostage in November 2012.