More than 6,000 blood donations are needed every day in the UK to treat patients in emergencies, and other people who have ongoing medical conditions such as blood disorders and cancers.
However the NHS Blood and Transplant service has reported that supplies are running low at many blood banks. Some of the shortfall is due to reduced donations during the recent cold spell - fewer people were able to travel to blood donation centres during the snowfall.
Now, the National Health Service is renewing appeals for members of the public to come forward to donate much needed blood.
One of the centres which is appealing for more donors is one in Oxfordshire, where donations are much needed. Cary Johnston met some of those helping to save lives including Gayle Franklin, Area manager, NHS Blood and Transplant; and Stephanie Danso, Blood transfusion recipient.
There are 23 blood donation centres in England, and the authorities are hoping to encourage people to pay a visit.
If you want to donate blood or find out more about the process you can telephone the NHS Blood & Transplant 24-hour hotline on 0300 123 23 23. You can also visit the Blood Donor website.