Stem cell breakthrough

Stem cell breakthrough could lead to new bone repair therapies.

Stem cell breakthrough

Scientists at the University of Southampton have created a new method to generate bone cells which could lead to revolutionary bone repair therapies for people with bone fractures or those who need hip replacement surgery due to osteoporosis and osteoarthritis.

To generate bone cells for regenerative medicine and further medical research remains a significant challenge. However we have found that by harnessing surface technologies that allow the generation and ultimately scale up of human embryonic stem cells to skeletal cells, we can aid the tissue engineering process. This is very exciting.

Our research may offer a whole new approach to skeletal regenerative medicine. The use of nanotopographical patterns could enable new cell culture designs and could herald the development of new bone repair therapies as well as further human stem cell research.

– Professor Richard Oreffo, University of Southampton

This latest discovery expands on the close collaborative work previously undertaken by the University of Southampton and the University of Glasgow. In 2011 the team successfully used plastic with embossed nanopatterns to grow and spread adult stem cells while keeping their stem cell characteristics