Nigel Farage has said he is overjoyed that at 1230pm today we will pass the point of no return for Brexit.
He tells our political reporter Phil Hornby that he still can't believe that it is about to happen.
An historical day today as the Prime Minister starts Brexit negotiations - however it is unchartered territory - and we are likely to see both winners and loses.
Mary Stanley went to a local market in Winchester to find out what stall holders are concerned about.
Calais is the first French town many British tourists encounter when they travel to the Continent by road, rail or ferry.
Mainland Europe is just 26 miles away from Dover when crossing the English Channel. But what do our continental neighbours think about us leaving the EU.
Tom Savvides has been finding out
Leaving the EU has raised massive concerns in Southampton - home to 25,000 Polish people.
Many moved to the city as far back as 2004. But already, recruitment agencies have seen the number of Eastern European workers plummet. Many say they're in limbo - waiting to see what happens.
Rachel Hepworth reports.
Craft beers are enjoying remarkable success - not least here in the South of England. The popularity of many of the brands is put down to the use of the distinctive of American hops. But the cost of importing those hops has soared after the pound fell following the vote for Brexit - an effect that is putting the craft ale revolution at risk. John Ryall reports.
The region's MPs heard the Government say it remains determined to trigger negotiations on the UK's withdrawal from the EU by the end of March.
MPs are set to debate the withdrawal bill over two full days. They get to vote on it on Wednesday evening. Our Political Correspondent Phil Hornby reports.
Clean. Soft. Hard. Red, white and blue. We're getting a better idea of what sort of Brexit we're heading to.
And we may be getting an idea of what destination the long-running Southern Trains dispute is heading to, as well. And Donald Trump - does he know where he's heading? The Dorchester ... in Southampton?
To discuss all this -
- Conservative Ed Vaizey MP, from Wantage in Oxfordshire;
- Baroness Jones of Moulsecoomb in Brighton from the Greens;
- Peter Kyle, Labour MP for Hove in Sussex
join Phil Hornby, our Political Correspondent
Kelly-Marie Blundell, the LibDem candidate for Lewes; Baroness Maggie Jones from Brighton for Labour; and John Howell, the Tory MP for Henley in Oxfordshire - debate the decision to choose Heathrow over Gatwick; the progress of Brexit; the Witney by-election; and the American Presidential election.
Tomorrow marks 100 days since Britain voted to leave the European Union. There's no doubt June the 23rd's decision was one of the biggest political shake-ups in history. In the South, almost 53 percent of people, more than 1 point 3 million, voted to leave. Gosport had the strongest 'leave' vote with 64 percent of people wanting OUT of the EU. Only 7 areas in the South voted to remain, including Hart, Brighton and Hove and Winchester. So how does the South feel about the EU result 100 days on? Here's Juliette Fletcher.