Mark Reckless, the UKIP MP for Rochester and Strood, challenged the Prime Minister to debate with Nigel Farage. Mr Cameron replied by accusing UKIP of wanting to privatise the NHS.
It's not the first time the Prime Minister has received a frosty reception.
But yesterday, the Witney MP endured a cold welcome of a different kind, as he ran in freezing conditions through Oxfordshire.
It was all part of the Great Brook Run - which takes place every year in Chadlington.
David Cameron was one of 140 runners who took part in the charity race and he's not a novice to the event, running in 2008, 2009 and 2012.
The run saw him wade through brooks in the Oxfordshire countryside before finishing off the race with a pint.
The Prime Minister visited the Thames Valley today to announce more than £40m of funding to help protect the region against future flooding.
Thousands of homes and businesses were destroyed after weeks of heavy rainfall earlier this year.
The two black boxes from flight MH17 have arrived in Farnborough six days after the crash which claimed almost 300 lives. As some of the bodies were flown to the Netherlands from the crash site in Ukraine - the Dutch government asked for the UK's help in analysing the plane's data. Kate Bunkall sends this report.
A Department for Transport spokesperson said: “We can confirm that the two black boxes from MH17 have been delivered by the Dutch Safety Board to the Air Accidents Investigation Branch at Farnborough for download.”
The black boxes from Malaysia Airlines flight MH17 have been delivered to the Air Accidents Investigation Branch (AAIB) headquarters at Farnborough in Hampshire, the AAIB has said.
The black box flight recorders from downed flight MH17 have arrived at the Air Accidents Investigation Branch in Farnborough in Hampshire the Ukraine government's investigation commission says.
David Cameron has been questioned on the percentage of women in his Cabinet during Prime Minister's Questions.
Given his commitment to equality, will the Prime Minister explain why 75% of his cabinet are still men.
Ed Miliband has spoken out about the Cabinet reshuffle during Prime Minister's Questions.
We have always said we would support the Government when they do the right thing so can I join thousands of parents across the country in congratulating him [David Cameron] on getting rid of the Education Secretary.
Michael Gove's wife Sarah Vine has tweeted a link to a Daily Mail article which criticised David Cameron's "sacking" of the former Education Secretary.
Mr Gove was moved from his education post to Chief Whip in yesterday's reshuffle, with the Prime Minister claiming he wanted "one of my big hitters, one of my real stars" in the position ahead of next year's General Election.
The Chief Whip also played down suggestions he was demoted, saying: "Demotion, emotion, promotion, locomotion, I don't know how you would describe this move - though move it is."
He also claimed Mr Cameron gave him the option of staying as the Education Secretary.