Police were called following the collision which took place in Onslow Street at lunchtime. The road remains partially closed after a black Ford S-Max was in collision with two pedestrians opposite South West Surrey Magistrate's Court.
One of the pedestrians has been taken to St George's Hospital in Tooting by air ambulance while the other pedestrian has been taken to the Royal Surrey County Hospital in Guildford with minor injuries.
Emergency services are still at the scene dealing with the incident and motorists are asked to avoid the area if possible for the time being.
A man has been jailed for life for murdering his mother's partner in Surrey last year. Joshua Ellis, who is 23 and from Guildford, will serve 14 years in prison. 54-year-old Neil Tulley's body was found with multiple stab wounds at the family home last August.
A body has been found in a flat in Guildford after emergency crews were called to reports of a fire just after 3am today. More than 30 firefighters tackled the blaze at a two-storey building on Berberis Close. An investigation is underway.
A 14-year-old boy has been sentenced to six years in prison following the murder of his mother's partner in the Bellfields area of Guildford last year.
At a previous hearing Jerome Ellis, was found guilty of the manslaughter of 54-year-old Neil Tulley on the grounds of loss of control.
His brother, 23-year-old Joshua Ellis was found guilty of the murder of Mr Tulley and will be sentenced next month.
During the trial the court heard that the victim's body was discovered with multiple stab wounds on the sofa at the family home on 13 August 2013.
A post mortem showed Mr Tulley had died after sustaining more than sixty stab wounds.
A police manhunt and public appeal was launched after the two brothers went missing following the fatal attack. They handed themselves in at Woking Police Station on the evening of Wednesday, 14 August 2013.
Video. It's been ranked outstanding by Oftsed and described by parents as unique. But now they fear a school in Surrey which caters for youngsters with complex special needs could be facing radical changes.
Plans to reorganise education for children with learning disabilities means the Gosden House school near Guildford would be converted to a secondary school only for pupils with a particular type of autism.
Our social affairs correspondent Christine Alsford spoke to Rowena Moore, Nicola Goswell and Penny Biggs, three parents whose children attend the school as well as Verona Perry's whose daughter Anna is making huge progress since attending Gosden House.
Christine also spoke to Laura Sabharwal, who is worried about her daughter losing her place in the single sex part of the school across the secondary years.
While there is a serious side to the floods, there are some people who have been taking advantage of the extra water everywhere, by having some fun.
Wakeboarders have been pictured surfing in Bedford Road underground car park in Guildford. Jorge Gill and Jack Hammersley used a winch and pulley system to pull the boards along at high speed between the concrete pillars.
Sandbags have been placed outside the Yvonne Arnaud Theatre in Guildford as the water level rose on the neighbouring River Wey in Surrey.
The search for a man who went missing from Porthleven on New Year's Day will resume just before midday.
The 27-year-old man from Guildford disappeared after going for a night swim with friends at Loe Bar.
The search was difficult yesterday because conditions were treacherous. Today's search will take place at low water.
A man in his 30s has been arrested on suspicion of possessing articles in relation to explosives.
The arrest comes following the cordon in Portsmouth Road and Ferry Lane in Guildford earlier this afternoon.