The visitors to the Madejski Stadium wilted in the late stages after losing captain Rob Jones to injury, and having already used their allocation of substitutes they were left exposed, allowing** **Reading to stretch their narrow lead to the final 4-1 comfortable margin of victory.
Reading went ahead early on when midfielder Danny Guthrie guided a long-range shot high into the roof of the net, but Doncaster levelled when substitute Theo Robinson latched on to a loose ball in the home area.
Reading regained their lead through Le Fondre before half-time and added two goals in the second half through Garath McCleary and Pavel Pogrebnyak.
Reading Football Club have purchased nearly 120 acres of land in Wokingham for the club's new training ground.
They exchanged contracts with the Royal Merchant Navy School Foundation for the land last Friday.
The site at Bearwood Estate will be home to both the first team and the Academy.
Plans have already been drawn up for 15 pithes and purpose-built indoor facilities, which will be submitted to Wokingham Borough Council in the near future.
The club have been at their current training ground at Hogwood Park since 2004.
The club say that a new training ground is seen as 'a hugely positive step in the right direction.'
Clarets striker Danny Ings scored his 11th goal of the season in all competitions in the 21st minute, firing in from Kieran Trippier's pass.
The hosts extended their advantage through Sam Vokes' eighth goal of the campaign in the 80th minute and while Jason Shackell's own-goal two minutes later made for a nervy finale, the home side managed to hold on.
he Birmingham goalkeeper was beaten again in the 75th minute. Dan Burn fouled Robson-Kanu on the edge of the area and Guthrie curled home a fine free-kick via Randolph's near post to complete** **Reading's comfortable win.
Full coverage of all today's fixtures on the ITV Sport website here
Birmingham failed to capitalise on their early superiority and Reading responded with a series of swift breaks. Garath McCleary released Pavel Pogrebnyak inside the Birmingham area but the Russian's fierce shot was well saved by Darren Randolph.
Reading's pressure finally paid off in the 32nd minute as they took the lead, albeit with a goal that was tinged with good fortune.
Chris Burke was penalised for handball and Guthrie's free-kick from wide on the left did not appear to carry too much danger. Yet it somehow found its way through a mass of bodies in the area and nestled in the far corner of Randolph's net.
Both of Guthrie's goals come from free-kicks - the first unintended, as it flew through a packed Birmingham penalty area, and the second an accurate set-piece that found the net via a post.
Those goals helped Reading make it 13 points from their last five league games and leave Birmingham unable to cap a memorable week with a third successive victory.
Lee Clark's men beat Sheffield Wednesday 4-1 in the league last time out and then followed that up with a 3-1 cup win over Swansea, and buoyed by those successes they started brightly.
Reading had won nine of their previous 11 games against Derby but came into the match with seven first-teamers missing, which meant a first league start for 19-year-old Jordan Obita.
The Royals had not conceded in 285 minutes of Championship football but their defence was almost breached in the eighth minute when Johnny Russell got in on the left and Alex McCarthy could only push out his low shot but Craig Bryson could not turn in the rebound.
The Russian striker found the net for the first time since January and although Will Hughes gave Derby hope, sub Nick Blackman secured Reading's 10th win in 12 games against Derby who have yet to record a home Sky Bet Championship victory this season.
Reading keeper Alex McCarthy kept the visitors in the game in the first half but Pogrebnyak pounced in the 47th minute after a free-kick was knocked down and the side-footed his second in the 62nd minute when Derby failed to clear a cross.
Hughes beat McCarthy with a curling shot in the 80th minute which was the first goal Reading had conceded in 365 minutes of Championship football but Blackman wrapped up the points in the fifth minute of stoppage time.
Yeovil again dictated proceedings at the start of the second half, with on-loan striker Andy Williams coming inches away from breaking the deadlock after hitting a curling effort narrowly wide.
However, Huish Park once again became the centre of controversy on 77 minutes after referee Trevor Kettle awarded the Royals a penalty after Luke Ayling was adjudged to have brought down Le Fondre.
The striker picked himself up and slammed past goalkeeper Wayne Hennessey to net his third league goal of the season and earn the visitors the valuable three points
In the first ever league meeting between the sides, Adam Le Fondre's penalty 13 minutes from time handed the Royals their first Sky Bet Championship win since the opening day - and condemned the Glovers to a fifth consecutive defeat in all competitions.
Reading manager Nigel Adkins made sweeping changes after the Royals' 6-0 humiliation at Peterborough United - with only Chris Gunter, Shaun Cummings and Le Fondre surviving the cull.
Adkins swapped Gareth McCleary for Danny Williams in a surprise first-half substitution and the newly-introduced midfielder came closest for the Royals before the break when he volleyed former Real Madrid and Everton winger Royston Drenthe's deep cross wide of the post.