Kerry Mitchell's mum died of breast cancer at just 46, but sadly this wasn't to be the only time it has affected her family.
In 2012 three weeks after her 40th birthday, Kerry, from Sussex, was diagnosed with breast cancer and has undergone treatment. .
Kerry's daughter Max has supported her through the treatment and together they are running the London Marathon for Breakthrough Breast Cancer.
Two years ago Lisa Tobin, 43, was diagnosed with Lymphangioleiomyomatosis (known as LAM), a progressive disease that destroys lung tissue and erodes lung function. There is currently no cure and little effective treatment.
Now her partner Mark Winter, 57, from Maidstone, is taking part in today's London Marathon and hopes to raise £2,000 for the charity LAM Action, that supports women like Lisa and funds vital research into the disease.
The Royal British Legion has a team of four women from Chichester running in this years London Marathon in a War Horse costume, to mark 100 years since the start of the First World War. They are also hoping to set the record for the "Fastest Marathon in a four person costume" on the day.
Sarah Gomme spoke to Penny Patten and Karen Shrimpton who are getting ready for the race this weekend.
The London Marathon is set to cause travel disruption across the capital this weekend.Read the full story ›
Ahead of the London Marathon on Sunday, we look at the best places to watch the action unfold along the 26-mile route.Read the full story ›
Thousands of runners will hit the streets of Sussex today for the fifth annual Brighton marathon.
World-record holder Paula Radcliffe will officially start the race. The event is expected to attract over 10 thousand runners.
It is recognised as one of the fastest half marathons in the country- and an ideal race for beginners. This weekend a record number - including Sports Correspondent Sarah Gomme - will take to the streets of Reading for the town's annual half marathon.