Despite the fact that Joanna Barker's mother was already being treated for ovarian cancer, when sister Sarah began to show symptoms no-one realised it was the same disease.
They died within six weeks of each other and to fight her grief Joanna, of Bray, Berkshire, founded the charity Target Ovarian Cancer, to raise awareness of the disease. Joanna has been awarded an MBE for her services to people with cancer
In the first three years of its existence, the charity has already trained several thousand GPs to spot early signs of the disease and has established an all-party parliamentary group in the House of Commons.
The initial findings of Target Ovarian Cancer's 'Pathfinder Study' demonstrate that the UK has among the worst survival rates for the disease in Europe, which has not changed in 30 years.
The study was intended to benchmark progress on fighting ovarian cancer with that achieved in other forms of cancer and to raise awareness of the disease.
The Queen’s Birthday Honours List is published in recognition of the achievements of a wide range of extraordinary people across the United Kingdom, from the Isles of Scilly up to the Scottish Highlands.
More than 1100 people have been recognised and while there are some famous names, the majority are people who have undertaken outstanding work in their communities.
There are roughly equal numbers of women and men on this Honours List (49% female) following New Year 2014, the first time ever that there had been more women on the list than men.
Among them are Joanna Barker, of Bray Berkshire, honoured for services to people with cancer, she founded the charity Target Ovarian Cancer.
Also honoured are Robin Aitken and Thomas Cairns, of Oxfordshire for their work as Co-Directors of Oxford Food Bank for services to Vulnerable People.
The Queen and the Duke of Edinburgh had an eventful day in Sussex visiting a brewery, a fish factory and a camping site!
The official visit was watched by hundreds of people who lined the streets to give them a rousing welcome.
Andrea Thomas has been following the day's proceedings.
Her Majesty The Queen and Prince Philip are visiting four locations in Sussex today.
Among the places to play host to the royal couple are Harvey's Brewery - the oldest independent brewery in Sussex; and the new archive for the University of Sussex.
Video. Windsor Castle has much to entice tourists inside its stone walls but outside in the grounds, there is a new attraction. Six willow arches have been constructed as a gift to the Queen, one for each decade she has been on the throne.
The coronation arches are now on display on the long walk at Windsor Great Park and has taken two months to complete. They were officially opened at the weekend. Divya Kohli reports.
A Daimler saloon car that used to belong to the Queen has sold at auction for £45,360 in Surrey. The guide price listed in the brochure was £25,000 - £30,000.
Her Majesty the Queen used the vehicle to travel between Windsor castle and Buckingham Palace.