Emergency services were called to a report of a lorry on fire in London Road, Brighton, near the junction with Carden Avenue, at 11am.
There are no reports of any other vehicles being involved or of any injuries. The fire was extinguished some 20 minutes later. The road was temporarily closed but by 1pm one lane was open in each direction.
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The RMT union has accused Southern of inventing figures which the company claims show record numbers of guards are going sick.
Thursday morning's weather for the west of the region
Thursday morning's weather for the east of the region