Oxford Brookes University's Gipsy Lane campus is without a water supply after a burst water main this morning.
Its sports centre will remain closed until further notice and other buildings may be affected.
A burst in the Old Road area of Headington, Oxford, was reported at around 6.30am and is affecting properties in the area which have either lost supply altogether or lost water pressure.
Thames Water has said it has isolated the stretch of pipe meaning there is no longer any water in it, but the pipe has not yet been fixed.
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Armed siege around property began just after 4pm this afternoon. A man, reported to be aged 72, is in the building and said to be armed