The M2 near Gillingham in Kent has been closed in both directions following a serious crash between a lorry and a car.
The motorway was shut to allow the Kent Air Ambulance to land.
Police say the road is not expected to be fully reopened until at least 4pm.
More top news
Friday's weather update with Simon Parkin
Thursday night's weather with Simon Parkin
Thursday afternoon's weather with Simon Parkin