The M2 near Gillingham in Kent has been closed in both directions following a serious crash between a lorry and a car.
The motorway was shut to allow the Kent Air Ambulance to land.
Police say the road is not expected to be fully reopened until at least 4pm.
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Friday's forecast for the west of the region
Friday's forecast for the east of the region
Extra support is on offer to help local reisdents in Dartford and Thurrock using the Dartford Crossing.