Four lorries have been involved in a multiple collision on the coastbound section of the M20 near junction 10, which occurred around midnight last night.
Two lorry drivers have been taken to the William Harvey Hospital with serious injuries.
The section between junctions 9 and 10 is expected to remain closed until after lunchtime while the investigation continues and the lorries and debris are cleared from the scene. A diversion is in place.
Anyone who witnessed the incident is asked to contact Kent Police on 01622 798538.
More top news
A school in Sussex has been chosen to pilot a new type of 'first aid' training for children's mental health
Tuesday night's weather for the west of the region
Tuesday night's weather for the east of the region