The Unite union has called Honda's decision to cut 800 jobs at its Swindon plant a 'hammer blow' to UK manufacturing and the local economy.
Unite national officer Tony Murphy said: "It's a tragedy for our members and their families.
"There's no doubt these cuts will have a significant knock-on impact on the supply chain, and on local shops and services .
"That is why we intend to save as many jobs as possible.
"Unite will oppose any compulsory job losses. We expect Honda to negotiate meaningfully with the union in order to mitigate the impact of these cuts.
"Unite will be meeting with our local union reps in the coming days to discuss the company's proposals."