The pollen count will increase as temperatures heat up and the worst conditions are expected on Sunday and Monday, according to forecasters.
Alexander Burkill, of the Met Office, said tree pollen would be more significant than grass pollen until the middle of May.
He said the tree pollen count will be high towards the end of the weekend, adding: "Today we've got a fair bit of cloud and the rain coming down, so it's going to go down to moderate.
Today and Monday in places, especially across England and especially in the south east, you're looking that it could get up to high."
More top news
James Wright has your evening forecast for the east of the region.
James Wright has the evening weather forecast for the west of the Meridian region.
A man who was hounded by the council over £8.62p claims he was forced to take his wife's ashes to the town hall to prove she had died.